UHRF1 monoclonal antibody (M02), clone 3B12
产品名称： UHRF1 monoclonal antibody (M02), clone 3B12
英文名称： UHRF1 monoclonal antibody (M02), clone 3B12
产品编号： H00029128-M02
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a partial recombinant UHRF1.
- Immunogen:
- UHRF1 (NP_037414, 694 a.a. ~ 793 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- WNEVLASLKDRPASGSPFQLFLSKVEETFQCICCQELVFRPITTVCQHNVCKDCLDRSFRAQVFSCPACRYDLGRSYAMQVNQPLQTVLNQLFPGYGNGR
- Host:
- Mouse
- Reactivity:
- Human
- Isotype:
- IgG1 Kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.74 KDa) .
- MSDS:
Download
- Applications
- Western Blot (Cell lysate)
- UHRF1 monoclonal antibody (M02), clone 3B12 Western Blot analysis of UHRF1 expression in MCF-7 ( Cat # L046V1 ).
- Protocol Download
- Western Blot (Recombinant protein)
- Protocol Download
- Immunofluorescence
enlarge this image- Immunofluorescence of monoclonal antibody to UHRF1 on MCF-7 cell . [antibody concentration 10 ug/ml]
- Protocol Download
- Sandwich ELISA (Recombinant protein)
- Detection limit for recombinant GST tagged UHRF1 is approximately 1ng/ml as a capture antibody.
- Protocol Download
- Entrez GeneID:
- 29128
- GeneBank Accession#:
- NM_013282
- Protein Accession#:
- NP_037414
- Gene Name:
- UHRF1
- Gene Alias:
- FLJ21925,ICBP90,MGC138707,Np95,RNF106,hNP95
- Gene Description:
- ubiquitin-like with PHD and ring finger domains 1
- Omim ID:
- 607990
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of a subfamily of RING-finger type E3 ubiquitin ligases. The protein binds to specific DNA sequences, and recruits a histone deacetylase to regulate gene expression. Its expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle. It plays a major role in the G1/S transition by regulating topoisomerase IIalpha and retinoblastoma gene expression, and functions in the p53-dependent DNA damage checkpoint. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- E3 ubiquitin-protein ligase UHRF1,RING finger protein 106,inverted CCAAT box-binding protein of 90 kDa,nuclear zinc finger protein Np95,transcription factor ICBP90,ubiquitin-like, containing PHD and RING finger domains, 1